4WUN

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4WUN_A

Chain 4WUN_B

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GENERAL

TITLE

STRUCTURE OF FGFR1 IN COMPLEX WITH AZD4547 (N-{3-[2-(3,5- DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5- DIMETHYLPIPERAZIN-1-YL]BENZAMIDE) AT 1.65 ANGSTROM

DATE LAST MODIFIED

22 Nov 2017

RELEASE

19 Nov 2014

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 1 2 1

RESOLUTION RANGE HIGH

1.65

RESOLUTION RANGE LOW

PUBMED ID

25760602

DOI

10.1107/S1399004714027539

PDBe

LIGANDS

568230

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P04859	FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR	ESCHERICHIA COLI	HUMAN	FGFR-1,BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1,B ...
	Q14839	FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR	ESCHERICHIA COLI	HUMAN	FGFR-1,BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1,B ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402