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GENERAL
TITLE
STRUCTURE OF FGFR1 IN COMPLEX WITH AZD4547 (N-{3-[2-(3,5- DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5- DIMETHYLPIPERAZIN-1-YL]BENZAMIDE) AT 1.65 ANGSTROM
DATE LAST MODIFIED
22 Nov 2017
RELEASE
19 Nov 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 1 2 1
RESOLUTION RANGE HIGH
1.65
RESOLUTION RANGE LOW
20
PUBMED ID
DOI
10.1107/S1399004714027539
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P11362 FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR ESCHERICHIA COLI HUMAN
FGFR-1,BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1,B ...
Mutations
P11362 FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR ESCHERICHIA COLI HUMAN
FGFR-1,BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1,B ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402