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GENERAL
TITLE
IDENTIFICATION OF A NOVEL FXR LIGAND THAT REGULATES METABOLISM
DATE LAST MODIFIED
27 Sept 2017
RELEASE
11 Feb 2015
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 21 21 21
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1038/NCOMMS2924
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q96RI1 NR1H4, BAR, FXR, HRR1, RIP14 ESCHERICHIA COLI BL21(DE3) HUMAN
FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ...
Mutations
Q96RI1 NR1H4, BAR, FXR, HRR1, RIP14 ESCHERICHIA COLI BL21(DE3) HUMAN
FARNESOID X-ACTIVATED RECEPTOR,FARNESOL RECEPTOR H ...
Mutations
O75376 -- -- HUMAN
N-COR1
Mutations
O75376 -- -- HUMAN
N-COR1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402