4X6P

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4X6P_A

Chain 4X6P_B

Spin

Focus

Transparency

More Info

GENERAL

TITLE

FACTOR XIA (PICHIA PASTORIS; C500S [C122S]) IN COMPLEX WITH THE INHIBITOR (2E)-N-{(1S)-1-[4-(3-AMINO-1H-INDAZOL-6-YL)-1H-IMIDAZOL-2- YL]-2-PHENYLETHYL}-3-[5-CHLORO-2-(1H-TETRAZOL-1-YL)PHENYL]PROP-2- ENAMIDE

DATE LAST MODIFIED

29 Jul 2020

RELEASE

18 Feb 2015

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 2 2 21

RESOLUTION RANGE HIGH

1.93

RESOLUTION RANGE LOW

41.27

PUBMED ID

25728130

DOI

10.1016/J.BMCL.2015.01.028

PDBe

4X6P

LIGANDS

829409 , 18119 , 628 , 49551

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P03951	F11	KOMAGATAELLA PASTORIS	HUMAN	FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA	Mutations
	P03951	F11	KOMAGATAELLA PASTORIS	HUMAN	FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402