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GENERAL
TITLE
ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH SQUARAMIDE COMPOUND 14 (N-[3,4-DIOXO-2-(4-{[4-(TRIFLUOROMETHYL)BENZYL]AMINO}PIPERIDIN-1-YL) CYCLOBUT-1-EN-1-YL]-3,5-DIMETHYL-1,2-OXAZOLE-4-SULFONAMIDE)
DATE LAST MODIFIED
25 Dec 2019
RELEASE
11 Mar 2015
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/TRANSCRIPTION INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.8
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.5B00050
PDBe
4YFN
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P09099 | RPOA, ECE24377A_3778 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ... | ||
| Q62696 | RPOA, ECE24377A_3778 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ... | ||
| P00918 | RPOB, ECE24377A_4528 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT BETA,RNA POLYMERASE SUBUNIT BETA,TRAN ... | ||
| P04925 | RPOC, ECE24377A_4529 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT BETA',RNA POLYMERASE SUBUNIT BETA',TR ... | ||
| P06463 | RPOZ, ECE24377A_4152 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP OMEGA SUBUNIT,RNA POLYMERASE OMEGA SUBUNIT,TR ... | ||
| P17312 | RPOD, ALT, B3067, JW3039 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI (STRAIN K12) | SIGMA-70 | ||
| Q62696 | RPOA, ECE24377A_3778 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ... | ||
| Q62696 | RPOA, ECE24377A_3778 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT ALPHA,RNA POLYMERASE SUBUNIT ALPHA,TR ... | ||
| A7ZUK1 | RPOB, ECE24377A_4528 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT BETA,RNA POLYMERASE SUBUNIT BETA,TRAN ... | Mutations | |
| P06463 | RPOC, ECE24377A_4529 | ESCHERICHIA COLI #1/H766 | ESCHERICHIA COLI O139:H28 (STRAIN E24377A / | RNAP SUBUNIT BETA',RNA POLYMERASE SUBUNIT BETA',TR ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402