4YHF

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4YHF_A

Chain 4YHF_B

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GENERAL

TITLE

BRUTON'S TYROSINE KINASE IN COMPLEX WITH A T-BUTYL CYANOACRYLAMIDE INHIBITOR

DATE LAST MODIFIED

24 Apr 2019

RELEASE

13 May 2015

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.2

RESOLUTION RANGE LOW

38.55

PUBMED ID

DOI

10.1038/NCHEMBIO.1817

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q06187	BTK, AGMX1, ATK, BPK	SPODOPTERA FRUGIPERDA	HUMAN	AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...	Mutations
	P00918	BTK, AGMX1, ATK, BPK	SPODOPTERA FRUGIPERDA	HUMAN	AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402