4YT6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4YT6_1

Chain 4YT6_H

Chain 4YT6_L

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GENERAL

TITLE

FACTOR VIIA IN COMPLEX WITH THE INHIBITOR 4-{[(R)-[5-ETHOXY-2-FLUORO- 3-(PROPAN-2-YLOXY)PHENYL](4-PHENYL-1H-IMIDAZOL-2-YL) METHYL]AMINO}BENZENECARBOXIMIDAMIDE

DATE LAST MODIFIED

13 May 2015

RELEASE

29 Apr 2015

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 41 21 2

RESOLUTION RANGE HIGH

2.07

RESOLUTION RANGE LOW

PUBMED ID

25881820

DOI

10.1016/J.BMCL.2015.03.062

PDBe

4YT6

LIGANDS

2912777 , 2692058 , 628 , 2730972

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P08709	F7	CRICETINAE	HUMAN	FACTOR VIIA HEAVY CHAIN, ACTIVATED FACTOR VIIA HEA ...	Mutations
	P08709	F7	CRICETINAE	HUMAN	FACTOR VIIA LIGHT CHAIN, PROCONVERTIN, SERUM PROTH ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402