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GENERAL
TITLE
WEAK TCR BINDING TO AN UNSTABLE INSULIN EPITOPE DRIVES TYPE 1 DIABETES
DATE LAST MODIFIED
12 Aug 2015
RELEASE
24 Jun 2015
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
182.23
PUBMED ID
DOI
10.1074/JBC.M114.622522
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P01902 H2-K1, H2-K ESCHERICHIA COLI BL21(DE3) HOUSE MOUSE
LEUKOCYTE ANTIGEN HEAVY CHAIN, H-2K(D)
Mutations
P61769 B2M, CDABP0092, HDCMA22P ESCHERICHIA COLI BL21(DE3) HUMAN -- Mutations
P01308 INS SYNTHETIC CONSTRUCT HUMAN -- Mutations
P01902 H2-K1, H2-K ESCHERICHIA COLI BL21(DE3) HOUSE MOUSE
LEUKOCYTE ANTIGEN HEAVY CHAIN, H-2K(D)
Mutations
P61769 B2M, CDABP0092, HDCMA22P ESCHERICHIA COLI BL21(DE3) HUMAN -- Mutations
P01308 INS SYNTHETIC CONSTRUCT HUMAN -- Mutations
P01902 H2-K1, H2-K ESCHERICHIA COLI BL21(DE3) HOUSE MOUSE
LEUKOCYTE ANTIGEN HEAVY CHAIN, H-2K(D)
Mutations
P61769 B2M, CDABP0092, HDCMA22P ESCHERICHIA COLI BL21(DE3) HUMAN -- Mutations
P01308 INS SYNTHETIC CONSTRUCT HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402