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GENERAL
TITLE
NOVEL BINDING SITE FOR ALLOSTERIC ACTIVATION OF AMPK
DATE LAST MODIFIED
27 Sept 2017
RELEASE
9 Mar 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.99
RESOLUTION RANGE LOW
48.66
PUBMED ID
DOI
10.1038/NCOMMS10912
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P54646 PRKAA2, AMPK, AMPK2 ESCHERICHIA COLI HUMAN AMPK SUBUNIT ALPHA-2,ACETYL-COA CARBOXYLASE KINASE,ACACAKINASE,HYDROXYMETHYLGLUTARYL-COA REDUCTASE KINASE,HMGCR KINASE HUMAN
AMPK SUBUNIT ALPHA-2,ACETYL-COA CARBOXYLASE KINASE ...
Mutations
Q9Y478 PRKAB1, AMPK ESCHERICHIA COLI HUMAN AMPKB HUMAN
AMPKB
Mutations
P54646 PRKAA2, AMPK, AMPK2 ESCHERICHIA COLI HUMAN AMPK SUBUNIT ALPHA-2,ACETYL-COA CARBOXYLASE KINASE,ACACAKINASE,HYDROXYMETHYLGLUTARYL-COA REDUCTASE KINASE,HMGCR KINASE HUMAN
AMPK SUBUNIT ALPHA-2,ACETYL-COA CARBOXYLASE KINASE ...
Mutations
Q9Y478 PRKAB1, AMPK ESCHERICHIA COLI HUMAN AMPKB HUMAN
AMPKB
Mutations
P54619 PRKAG1 ESCHERICHIA COLI HUMAN AMPKG HUMAN
AMPKG
Mutations
P54619 PRKAG1 ESCHERICHIA COLI HUMAN AMPKG HUMAN
AMPKG
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402