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GENERAL
TITLE
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM265
DATE LAST MODIFIED
11 Dec 2019
RELEASE
29 Jul 2015
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
44.1
PUBMED ID
DOI
10.1126/SCITRANSLMED.AAA6645

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08210 PFF0160C ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) DHODEHASE,DIHYDROOROTATE OXIDASE PLASMODIUM FALCIPARUM (ISOLATE 3D7)
DHODEHASE,DIHYDROOROTATE OXIDASE
Mutations
Q08210 PFF0160C ESCHERICHIA COLI PLASMODIUM FALCIPARUM (ISOLATE 3D7) DHODEHASE,DIHYDROOROTATE OXIDASE PLASMODIUM FALCIPARUM (ISOLATE 3D7)
DHODEHASE,DIHYDROOROTATE OXIDASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402