5HEZ

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5HEZ_5

Chain 5HEZ_A

Chain 5HEZ_B

Chain 5HEZ_C

Chain 5HEZ_D

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GENERAL

TITLE

JAK2 KINASE (JH1 DOMAIN) MUTANT P1057A IN COMPLEX WITH TG101209

DATE LAST MODIFIED

16 Nov 2016

RELEASE

9 Nov 2016

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 2 2 2

RESOLUTION RANGE HIGH

2.66

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1126/SCITRANSLMED.AAG1974

PDBe

LIGANDS

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
F8WQK8	JAK2	SPODOPTERA FRUGIPERDA	HUMAN	JANUS KINASE 2,JAK-2
O60674	JAK2	SPODOPTERA FRUGIPERDA	HUMAN	JANUS KINASE 2,JAK-2	Mutations
P31947	JAK2	SPODOPTERA FRUGIPERDA	HUMAN	JANUS KINASE 2,JAK-2
Q9BWG4	JAK2	SPODOPTERA FRUGIPERDA	HUMAN	JANUS KINASE 2,JAK-2

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402