5HS3

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5HS3_1

Bioassembly 5HS3_2

Bioassembly 5HS3_3

Chain 5HS3_A

Chain 5HS3_B

Chain 5HS3_C

Chain 5HS3_D

Chain 5HS3_E

Chain 5HS3_F

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GENERAL

TITLE

HUMAN THYMIDYLATE SYNTHASE COMPLEXED WITH DUMP AND 3-AMINO-2-BENZOYL- 4-METHYLTHIENO[2,3-B]PYRIDIN-6-OL

DATE LAST MODIFIED

19 Feb 2020

RELEASE

24 Feb 2016

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 43 21 2

RESOLUTION RANGE HIGH

3.1

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/NCOMMS11040

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P63092	TYMS, TS	ESCHERICHIA COLI	HUMAN	TSASE
P04818	TYMS, TS	ESCHERICHIA COLI	HUMAN	TSASE	Mutations
P06126	TYMS, TS	ESCHERICHIA COLI	HUMAN	TSASE
P61769	TYMS, TS	ESCHERICHIA COLI	HUMAN	TSASE
P04818	TYMS, TS	ESCHERICHIA COLI	HUMAN	TSASE	Mutations
P04818	TYMS, TS	ESCHERICHIA COLI	HUMAN	TSASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402