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GENERAL
TITLE
DISCOVERY OF NOVEL, ORALLY EFFICACIOUS LIVER X RECEPTOR (LXR) BETA AGONISTS
DATE LAST MODIFIED
-
RELEASE
29 Jun 2016
OBSOLETE
CLASSIFICATION
DNA BINDING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.609
RESOLUTION RANGE LOW
82.67
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.5B02029
PDBe
5I4V
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q15596 | NR1H2, LXRB, NER, UNR, NCOA2, BHLHE75, SRC2, TIF2 | ESCHERICHIA COLI | HUMAN | LIVER X RECEPTOR BETA,NUCLEAR RECEPTOR NER,NUCLEAR ... | Mutations | |
| P00720 | RXRB, NR2B2, NCOA2, BHLHE75, SRC2, TIF2 | ESCHERICHIA COLI | HUMAN | NUCLEAR RECEPTOR SUBFAMILY 2 GROUP B MEMBER 2,RETI ... | ||
| Q15596 | NR1H2, LXRB, NER, UNR, NCOA2, BHLHE75, SRC2, TIF2 | ESCHERICHIA COLI | HUMAN | LIVER X RECEPTOR BETA,NUCLEAR RECEPTOR NER,NUCLEAR ... | Mutations | |
| Q15596 | RXRB, NR2B2, NCOA2, BHLHE75, SRC2, TIF2 | ESCHERICHIA COLI | HUMAN | NUCLEAR RECEPTOR SUBFAMILY 2 GROUP B MEMBER 2,RETI ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402