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GENERAL
TITLE
STRUCTURE OF THE PRIMARY ONCOGENIC MUTANT Y641N HS/ACPRC2 IN COMPLEX WITH A PYRIDONE INHIBITOR
DATE LAST MODIFIED
22 Nov 2017
RELEASE
4 May 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.98
RESOLUTION RANGE LOW
115.13
PUBMED ID
DOI
10.1038/NCOMMS11384
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q15910 EZH2, EZH2, KMT6 SPODOPTERA FRUGIPERDA GREEN ANOLE, HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Mutations
Q15910 EZH2, EZH2, KMT6 SPODOPTERA FRUGIPERDA GREEN ANOLE, HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Mutations
O75530 EED SPODOPTERA FRUGIPERDA HUMAN
HEED,WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLAS ...
Mutations
P0C6U8-Nsp3 EED SPODOPTERA FRUGIPERDA HUMAN
HEED,WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLAS ...
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 SPODOPTERA FRUGIPERDA HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
P0C6X7-Nsp3 SUZ12, CHET9, JJAZ1, KIAA0160 SPODOPTERA FRUGIPERDA HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402