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GENERAL
TITLE
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR C49 (2-{[(2-{[(E)-2- (DIMETHYLAMINO)ETHENYL](ETHYL)AMINO}-2-OXOETHYL) AMINO]METHYL}PYRIDINE-4-CARBOXYLIC ACID)
DATE LAST MODIFIED
25 Dec 2019
RELEASE
27 Jul 2016
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.69
RESOLUTION RANGE LOW
35.1
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2016.06.006
PDBe
5ISL
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q7NDN8 | KDM5A, JARID1A, RBBP2, RBP2 | ESCHERICHIA COLI | HUMAN | HISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CO ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402