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GENERAL
TITLE
STRUCTURAL BASIS FOR TSLP ANTAGONISM BY THE THERAPEUTIC ANTIBODY TEZEPELUMAB (MEDI9929 / AMG-157)
DATE LAST MODIFIED
28 Feb 2018
RELEASE
5 Apr 2017
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 1 2
RESOLUTION RANGE HIGH
2.298
RESOLUTION RANGE LOW
55
PUBMED ID
DOI
10.1038/NCOMMS14937
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q969D9 TSLP ESCHERICHIA COLI BL21(DE3) HUMAN -- Mutations
-- HOMO SAPIENS HUMAN --
-- HOMO SAPIENS HUMAN --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402