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GENERAL
TITLE
STRUCTURE OF HUMAN NPC1 MIDDLE LUMENAL DOMAIN BOUND TO NPC2
DATE LAST MODIFIED
29 Jul 2020
RELEASE
24 Aug 2016
OBSOLETE
CLASSIFICATION
TRANSPORT PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.1611956113
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O15118 NPC1 BACTERIA HUMAN -- HUMAN -- Mutations
O15118 NPC1 BACTERIA HUMAN -- HUMAN -- Mutations
P61916 NPC2, HE1 HOMO SAPIENS HUMAN HUMAN EPIDIDYMIS-SPECIFIC PROTEIN 1,HE1,NIEMANN-PICK DISEASETYPE C2 PROTEIN HUMAN
HUMAN EPIDIDYMIS-SPECIFIC PROTEIN 1,HE1,NIEMANN-PI ...
Mutations
P61916 NPC2, HE1 HOMO SAPIENS HUMAN HUMAN EPIDIDYMIS-SPECIFIC PROTEIN 1,HE1,NIEMANN-PICK DISEASETYPE C2 PROTEIN HUMAN
HUMAN EPIDIDYMIS-SPECIFIC PROTEIN 1,HE1,NIEMANN-PI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402