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5L9V

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GENERAL
TITLE
HIF PROLYL HYDROXYLASE 2 (PHD2-R281C/P317C) CROSS-LINKED TO HIF-1ALPHA NODD-L397C/D412C AND N-OXALYLGLYCINE (NOG) (COMPLEX-1)
DATE LAST MODIFIED
29 Nov 2017
RELEASE
31 Aug 2016
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.829
RESOLUTION RANGE LOW
43.8
PUBMED ID
DOI
10.1038/NCOMMS12673

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9GZT9 EGLN1, C1ORF12, PNAS-118, PNAS-137 ESCHERICHIA COLI HUMAN HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2,HPH-2,PROLYLHYDROXYLASE DOMAIN-CONTAINING PROTEIN 2,PHD2,SM-20 HUMAN
HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2,HPH- ...
Mutations
Q9GZT9 EGLN1, C1ORF12, PNAS-118, PNAS-137 ESCHERICHIA COLI HUMAN HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2,HPH-2,PROLYLHYDROXYLASE DOMAIN-CONTAINING PROTEIN 2,PHD2,SM-20 HUMAN
HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE 2,HPH- ...
Mutations
Q16665 -- -- HUMAN HIF1-ALPHA,ARNT-INTERACTING PROTEIN,BASIC-HELIX-LOOP-HELIX-PAS PROTEIN MOP1,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 78,BHLHE78,MEMBER OF PAS PROTEIN 1,PAS DOMAIN-CONTAINING PROTEIN 8 HUMAN
HIF1-ALPHA,ARNT-INTERACTING PROTEIN,BASIC-HELIX-LO ...
Mutations
Q16665 -- -- HUMAN HIF1-ALPHA,ARNT-INTERACTING PROTEIN,BASIC-HELIX-LOOP-HELIX-PAS PROTEIN MOP1,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 78,BHLHE78,MEMBER OF PAS PROTEIN 1,PAS DOMAIN-CONTAINING PROTEIN 8 HUMAN
HIF1-ALPHA,ARNT-INTERACTING PROTEIN,BASIC-HELIX-LO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402