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GENERAL
TITLE
STRUCTURE OF THE EPIGENETIC ONCOGENE MMSET AND INHIBITION BY N-ALKYL SINEFUNGIN DERIVATIVES
DATE LAST MODIFIED
16 Oct 2019
RELEASE
5 Oct 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.05
RESOLUTION RANGE LOW
61.86
PUBMED ID
DOI
10.1021/ACSCHEMBIO.6B00308

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9BYW2 SETD2, HIF1, HYPB, KIAA1732, KMT3A, SET2, HSPC069 ESCHERICHIA COLI BL21(DE3) HUMAN HIF-1,HUNTINGTIN YEAST PARTNER B,HUNTINGTIN-INTERACTINGPROTEIN 1,HIP-1,HUNTINGTIN-INTERACTING PROTEIN B,LYSINE N-METHYLTRANSFERASE 3A,SET DOMAIN-CONTAINING PROTEIN 2,HSET2,P231HBP HUMAN
HIF-1,HUNTINGTIN YEAST PARTNER B,HUNTINGTIN-INTERA ...
Mutations
Q9BYW2 SETD2, HIF1, HYPB, KIAA1732, KMT3A, SET2, HSPC069 ESCHERICHIA COLI BL21(DE3) HUMAN HIF-1,HUNTINGTIN YEAST PARTNER B,HUNTINGTIN-INTERACTINGPROTEIN 1,HIP-1,HUNTINGTIN-INTERACTING PROTEIN B,LYSINE N-METHYLTRANSFERASE 3A,SET DOMAIN-CONTAINING PROTEIN 2,HSET2,P231HBP HUMAN
HIF-1,HUNTINGTIN YEAST PARTNER B,HUNTINGTIN-INTERA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402