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GENERAL
TITLE
DISCOVERY OF PHENOXYINDAZOLES AND PHENYLTHIOINDAZOLES AS RORG INVERSE AGONISTS
DATE LAST MODIFIED
7 Dec 2016
RELEASE
16 Nov 2016
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
H 3 2
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
29.313
PUBMED ID
DOI
10.1016/J.BMCL.2016.10.023
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P51449 RORC, NR1F3, RORG, RZRG ESCHERICHIA COLI HUMAN NUCLEAR RECEPTOR RZR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1GROUP F MEMBER 3,RAR-RELATED ORPHAN RECEPTOR C,RETINOID-RELATEDORPHAN RECEPTOR-GAMMA HUMAN
NUCLEAR RECEPTOR RZR-GAMMA,NUCLEAR RECEPTOR SUBFAM ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402