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GENERAL
TITLE
STRUCTURE OF GLUK1 LIGAND-BINDING DOMAIN (S1S2) IN COMPLEX WITH (2S, 4R)-4-(2-CARBOXYPHENOXY)PYRROLIDINE-2-CARBOXYLIC ACID AT 3.18 A RESOLUTION
DATE LAST MODIFIED
9 Aug 2017
RELEASE
11 Jan 2017
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
3.18
RESOLUTION RANGE LOW
29.75
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B01516
PDBe
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Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P22756 | GRIK1, GLUR5 | ESCHERICHIA COLI BL21(DE3) | NORWAY RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE RECEPTOR 5,GLUR5CRYSTALLIZED IS THE EXTRACELLULAR LIGAND-BINDING DOMAIN OF GLUK1.TRANSMEMBRANE REGIONS WERE GENETICALLY REMOVED AND REPLACED WITH AGLY-THR LINKER (RESIDUE 117-118). THE SEQUENCE MATCHES DISCONTINOUSLYWITH REFERENCE DATABASE (430-544, 667-805). GLY1 IS A CLONINGREMNANCE. ISOFORM GLUR5-2. THE CONFLICT OF GLY34 IS REFERED TO ALA -GLY SEQUENCE CONFLICT AT RESIDUE 462 IN UNP DATABASE | NORWAY RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE R ... | Mutations | |
| P22756 | GRIK1, GLUR5 | ESCHERICHIA COLI BL21(DE3) | NORWAY RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE RECEPTOR 5,GLUR5CRYSTALLIZED IS THE EXTRACELLULAR LIGAND-BINDING DOMAIN OF GLUK1.TRANSMEMBRANE REGIONS WERE GENETICALLY REMOVED AND REPLACED WITH AGLY-THR LINKER (RESIDUE 117-118). THE SEQUENCE MATCHES DISCONTINOUSLYWITH REFERENCE DATABASE (430-544, 667-805). GLY1 IS A CLONINGREMNANCE. ISOFORM GLUR5-2. THE CONFLICT OF GLY34 IS REFERED TO ALA -GLY SEQUENCE CONFLICT AT RESIDUE 462 IN UNP DATABASE | NORWAY RAT | GLUK1,GLUTAMATE RECEPTOR 5,GLUR5,GLUK1,GLUTAMATE R ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402