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GENERAL
TITLE
STRUCTURE OF HUMAN O-GLCNAC HYDROLASE WITH NEW IMINOCYCLITOL TYPE INHIBITOR
DATE LAST MODIFIED
30 Aug 2017
RELEASE
29 Mar 2017
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43 21 2
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
95.56
PUBMED ID
DOI
10.1038/NCHEMBIO.2358
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60502 MGEA5, HEXC, KIAA0679, MEA5 ESCHERICHIA COLI BL21(DE3) HUMAN OGA,BETA-N-ACETYLGLUCOSAMINIDASE,BETA-N-ACETYLHEXOSAMINIDASE,BETA-HEXOSAMINIDASE,MENINGIOMA-EXPRESSED ANTIGEN5,N-ACETYL-BETA-D-GLUCOSAMINIDASE,N-ACETYL-BETA-GLUCOSAMINIDASE,NUCLEAR CYTOPLASMIC O-GLCNACASE AND ACETYLTRANSFERASE,NCOAT HUMAN
OGA,BETA-N-ACETYLGLUCOSAMINIDASE,BETA-N-ACETYLHEXO ...
Mutations
O60502 MGEA5, HEXC, KIAA0679, MEA5 ESCHERICHIA COLI BL21(DE3) HUMAN OGA,BETA-N-ACETYLGLUCOSAMINIDASE,BETA-N-ACETYLHEXOSAMINIDASE,BETA-HEXOSAMINIDASE,MENINGIOMA-EXPRESSED ANTIGEN5,N-ACETYL-BETA-D-GLUCOSAMINIDASE,N-ACETYL-BETA-GLUCOSAMINIDASE,NUCLEAR CYTOPLASMIC O-GLCNACASE AND ACETYLTRANSFERASE,NCOAT HUMAN
OGA,BETA-N-ACETYLGLUCOSAMINIDASE,BETA-N-ACETYLHEXO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402