5NEB logo

5NEB

3D Structure View

Loading...

More Info

GENERAL
TITLE
STRUCTURE OF GLUK1 LIGAND-BINDING DOMAIN (S1S2) IN COMPLEX WITH LM-12B AT 2.05 A RESOLUTION
DATE LAST MODIFIED
7 Mar 2018
RELEASE
26 Jul 2017
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.05
RESOLUTION RANGE LOW
87.216
PUBMED ID
DOI
10.1021/ACSCHEMNEURO.7B00201
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P22756 GRIK1, GLUR5 ESCHERICHIA COLI BL21(DE3) RAT GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTALLIZED IS THE EXTRACELLULAR LIGAND-BINDING DOMAINOF GLUK1. TRANSMEMBRANE REGIONS WERE REPLACED WITH A GLY-THR LINKER(RESIDUES 117-118). THE SEQUENCE MATCHES DISCONTINOUSLY WITHREFERENCE DATABASE (430-544, 667-805). THERE IS A SEQUENCE CONFLICTAT RESIDUE 34 (462) OF THE CRYSTALLIZED PROTEIN DUE TO DIFFERENCES INDATABASE SEQUENCE (SEE GENBANK ACCESION NO.AAA02874). GLY1 IS ACLONING REMNANT. RAT
GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTA ...
Mutations
P22756 GRIK1, GLUR5 ESCHERICHIA COLI BL21(DE3) RAT GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTALLIZED IS THE EXTRACELLULAR LIGAND-BINDING DOMAINOF GLUK1. TRANSMEMBRANE REGIONS WERE REPLACED WITH A GLY-THR LINKER(RESIDUES 117-118). THE SEQUENCE MATCHES DISCONTINOUSLY WITHREFERENCE DATABASE (430-544, 667-805). THERE IS A SEQUENCE CONFLICTAT RESIDUE 34 (462) OF THE CRYSTALLIZED PROTEIN DUE TO DIFFERENCES INDATABASE SEQUENCE (SEE GENBANK ACCESION NO.AAA02874). GLY1 IS ACLONING REMNANT. RAT
GLUK1,GLUTAMATE RECEPTOR 5,GLUR5THE PROTEIN CRYSTA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402