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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ACTIVIN RECEPTOR TYPE-2A LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV
DATE LAST MODIFIED
29 Jul 2020
RELEASE
15 Nov 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.35
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1073/PNAS.1707925114
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P27037 ACVR2A, ACVR2 HOMO SAPIENS HUMAN ACTIVIN RECEPTOR TYPE IIA,ACTRIIA HUMAN
ACTIVIN RECEPTOR TYPE IIA,ACTRIIA
Mutations
P27037 ACVR2A, ACVR2 HOMO SAPIENS HUMAN ACTIVIN RECEPTOR TYPE IIA,ACTRIIA HUMAN
ACTIVIN RECEPTOR TYPE IIA,ACTRIIA
Mutations
-- -- HUMAN MOR08159_GERMLINED FV HUMAN
MOR08159_GERMLINED FV
-- -- HUMAN MOR08159_GERMLINED FV HUMAN
MOR08159_GERMLINED FV
P01704 -- -- HUMAN MOR08159_GERMLINED FV HUMAN
MOR08159_GERMLINED FV
P01704 -- -- HUMAN MOR08159_GERMLINED FV HUMAN
MOR08159_GERMLINED FV
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402