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GENERAL
TITLE
HUMAN N-MYRISTOYLTRANSFERASE 1 (MNT1) WITH MYRISTOYL-COA ANALOGUE X10 BOUND
DATE LAST MODIFIED
6 Jun 2018
RELEASE
30 May 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
2.37
RESOLUTION RANGE LOW
177.454
PUBMED ID
-
DOI
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P30419 NMT1, NMT ESCHERICHIA COLI BL21(DE3) HUMAN MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE 1,TYPE I N-MYRISTOYLTRANSFERASE,PEPTIDE N-MYRISTOYLTRANSFERASE 1FOLLOWED BY A 3C PROTEASE SITE. THE HIS-TAG WAS CLEAVED WITH 3CPROTEASE FOR CRYSTALLIZATION LEAVING 3 RESIDUES THAT ARE FOLLOWED BY109-496 AMINO ACIDS OF THE NMT1. THE 3 RESIDUES PRECEDING THE NMT1WERE NOT MODELED AS THEY WERE FLEXIBLE AND NOT OBSERVED IN THEELECTRON DENSITY MAP. RESIDUES 109-114, 182-188, 308-319 AND 407-414OF THE NMT1 CHAIN A AND RESIDUES 109-114 AND 312-318 OF THE NMT1CHAIN B WERE NOT MODELED BECAUSE THEY WERE DISORDERED AND CANNOT BESEEN IN THE ELECTRON DENSITY MAP. HUMAN
MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE 1,TYP ...
Mutations
P30419 NMT1, NMT ESCHERICHIA COLI BL21(DE3) HUMAN MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE 1,TYPE I N-MYRISTOYLTRANSFERASE,PEPTIDE N-MYRISTOYLTRANSFERASE 1FOLLOWED BY A 3C PROTEASE SITE. THE HIS-TAG WAS CLEAVED WITH 3CPROTEASE FOR CRYSTALLIZATION LEAVING 3 RESIDUES THAT ARE FOLLOWED BY109-496 AMINO ACIDS OF THE NMT1. THE 3 RESIDUES PRECEDING THE NMT1WERE NOT MODELED AS THEY WERE FLEXIBLE AND NOT OBSERVED IN THEELECTRON DENSITY MAP. RESIDUES 109-114, 182-188, 308-319 AND 407-414OF THE NMT1 CHAIN A AND RESIDUES 109-114 AND 312-318 OF THE NMT1CHAIN B WERE NOT MODELED BECAUSE THEY WERE DISORDERED AND CANNOT BESEEN IN THE ELECTRON DENSITY MAP. HUMAN
MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE 1,TYP ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402