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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE ACVR1 (ALK2) KINASE IN COMPLEX WITH LDN- 212854
DATE LAST MODIFIED
4 Apr 2018
RELEASE
20 Sept 2017
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 1 2 1
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
65.65
PUBMED ID
DOI
10.1016/J.BONE.2017.09.004

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-I HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-I HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-I HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
Q04771 ACVR1, ACVRLK2 SPODOPTERA FRUGIPERDA HUMAN ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LIKE KINASE2,ALK-2,SERINE/THREONINE-PROTEIN KINASE RECEPTOR R1,SKR1,TGF-BSUPERFAMILY RECEPTOR TYPE I,TSR-I HUMAN
ACTIVIN RECEPTOR TYPE I,ACTR-I,ACTIVIN RECEPTOR-LI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402