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GENERAL
TITLE
CRYSTAL STRUCTURE OF PLK1 IN COMPLEX WITH A NOVEL 5,6- DIHYDROIMIDAZOLO[1,5-F]PTERIDINE INHIBITOR.
DATE LAST MODIFIED
8 Mar 2017
RELEASE
22 Feb 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2016.10.009
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P53350 PLK1, PLK UNIDENTIFIED BACULOVIRUS HUMAN POLO-LIKE KINASE 1,PLK-1,SERINE/THREONINE-PROTEIN KINASE 13,STPK13 HUMAN
POLO-LIKE KINASE 1,PLK-1,SERINE/THREONINE-PROTEIN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402