5W0I logo

5W0I

3D Structure View

Loading...

More Info

GENERAL
TITLE
CREBBP BROMODOMAIN IN COMPLEX WITH CPD8 (1-(3-(7-(DIFLUOROMETHYL)-6- (1-METHYL-1H-PYRAZOL-4-YL)-3,4-DIHYDROQUINOLIN-1(2H)-YL)-1- (TETRAHYDROFURAN-3-YL)-1,4,6,7-TETRAHYDRO-5H-PYRAZOLO[4,3-C]PYRIDIN- 5-YL)ETHAN-1-ONE)
DATE LAST MODIFIED
-
RELEASE
7 Mar 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.43
RESOLUTION RANGE LOW
31.06
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B00796
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P45481 CREBBP, CBP ESCHERICHIA COLI MOUSE -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402