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GENERAL
TITLE
CRYSTAL STRUCTURE OF WNK1 IN COMPLEX WITH N-{(3R)-1-[(4-CHLOROPHENYL) METHYL]PYRROLIDIN-3-YL}-2-(3-METHOXYPHENYL)-N-METHYLQUINOLINE-4- CARBOXAMIDE (COMPOUND 8)
DATE LAST MODIFIED
6 Sept 2017
RELEASE
16 Aug 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B00708

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q9H4A3 WNK1, HSN2, KDP, KIAA0344, PRKWNK1 ESCHERICHIA COLI HUMAN
ERYTHROCYTE 65 KDA PROTEIN, P65, KINASE DEFICIENT ...
Mutations
Q9H4A3 WNK1, HSN2, KDP, KIAA0344, PRKWNK1 ESCHERICHIA COLI HUMAN
ERYTHROCYTE 65 KDA PROTEIN, P65, KINASE DEFICIENT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402