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GENERAL
TITLE
CRYSTAL STRUCTURE OF GLUTAMINASE C IN COMPLEX WITH INHIBITOR 2-PHENYL- N-{5-[4-({5-[(PHENYLACETYL)AMINO]-1,3,4-THIADIAZOL-2-YL}AMINO) PIPERIDIN-1-YL]-1,3,4-THIADIAZOL-2-YL}ACETAMIDE (UPGL-00004)
DATE LAST MODIFIED
1 Jan 2020
RELEASE
10 Jan 2018
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.445
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1074/JBC.M117.810101
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O94925 GLS, GLS1, KIAA0838 ESCHERICHIA COLI HUMAN
GLS,K-GLUTAMINASE, L-GLUTAMINE AMIDOHYDROLASE
Mutations
O94925 GLS, GLS1, KIAA0838 ESCHERICHIA COLI HUMAN
GLS,K-GLUTAMINASE, L-GLUTAMINE AMIDOHYDROLASE
Mutations
O94925 GLS, GLS1, KIAA0838 ESCHERICHIA COLI HUMAN
GLS,K-GLUTAMINASE, L-GLUTAMINE AMIDOHYDROLASE
Mutations
O94925 GLS, GLS1, KIAA0838 ESCHERICHIA COLI HUMAN
GLS,K-GLUTAMINASE, L-GLUTAMINE AMIDOHYDROLASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402