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GENERAL
TITLE
THE CRYO-EM STRUCTURE OF THE PRECUSOR OF HUMAN PRE-CATALYTIC SPLICEOSOME (PRE-B COMPLEX)
DATE LAST MODIFIED
14 Oct 2020
RELEASE
14 Nov 2018
OBSOLETE
CLASSIFICATION
SPLICING
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
5.7
RESOLUTION RANGE LOW
5.7
PUBMED ID
DOI
10.1038/S41422-018-0094-7
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O75533 -- -- HUMAN
PRE-MRNA-SPLICING FACTOR SF3B 155 KDA SUBUNIT,SF3B ...
Mutations
Q13435 -- -- HUMAN
PRE-MRNA-SPLICING FACTOR SF3B 145 KDA SUBUNIT,SF3B ...
Mutations
Q15393 -- -- HUMAN
PRE-MRNA-SPLICING FACTOR SF3B 130 KDA SUBUNIT,SF3B ...
Mutations
Q15427 -- -- HUMAN
PRE-MRNA-SPLICING FACTOR SF3B 49 KDA SUBUNIT,SPLIC ...
Mutations
Q9Y3B4 -- -- HUMAN
PRE-MRNA BRANCH SITE PROTEIN P14,SF3B 14 KDA SUBUN ...
Mutations
Q7RTV0 -- -- HUMAN
PHD FINGER-LIKE DOMAIN PROTEIN 5A,SPLICING FACTOR ...
Mutations
Q9BWJ5 -- -- HUMAN
SF3B5,PRE-MRNA-SPLICING FACTOR SF3B 10 KDA SUBUNIT ...
Mutations
Q6P2Q9 -- -- HUMAN
220 KDA U5 SNRNP-SPECIFIC PROTEIN,PRP8 HOMOLOG,SPL ...
Mutations
-- -- HUMAN --
Q15029 -- -- HUMAN
ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402