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GENERAL
TITLE
CRYSTAL STRUCTURE OF AN N-HYDROXYTHIENOPYRIMIDINE-2,4-DIONE RNASE H ACTIVE SITE INHIBITOR WITH MULTIPLE BINDING MODES TO HIV REVERSE TRANSCRIPTASE
DATE LAST MODIFIED
11 Dec 2019
RELEASE
8 Aug 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE / TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
1.8
RESOLUTION RANGE LOW
55.32
PUBMED ID
DOI
10.1016/J.EJMECH.2017.09.054

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03366 GAG-POL ESCHERICHIA COLI BL21(DE3) HIV-1 -- Mutations
P03366 GAG-POL ESCHERICHIA COLI BL21(DE3) HIV-1
EXORIBONUCLEASE H, P66 RT
Mutations
P03366 GAG-POL ESCHERICHIA COLI BL21(DE3) HIV-1 -- Mutations
P03366 GAG-POL ESCHERICHIA COLI BL21(DE3) HIV-1
EXORIBONUCLEASE H, P66 RT
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402