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GENERAL
TITLE
STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC CO-ACTIVATOR PEPTIDE AND COMPOUND 25A AKA BICYCLIC HEXAFLUOROISOPROPYL 2 ALCOHOL SULFONAMIDES
DATE LAST MODIFIED
3 Jan 2018
RELEASE
20 Dec 2017
OBSOLETE
CLASSIFICATION
NUCLEAR PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.56
RESOLUTION RANGE LOW
45.54
PUBMED ID
DOI
10.1016/J.BMCL.2017.12.006
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O75469 NR1I2, PXR, NCOA1, BHLHE74, SRC1 ESCHERICHIA COLI HUMAN
ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPT ...
Mutations
O75469 NR1I2, PXR, NCOA1, BHLHE74, SRC1 ESCHERICHIA COLI HUMAN
ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402