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GENERAL
TITLE
CRYSTAL STRUCTURE OF KRAS A146T-GDP DEMONSTRATING OPEN SWITCH 1 CONFORMATION
DATE LAST MODIFIED
19 Jun 2019
RELEASE
22 May 2019
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 3
RESOLUTION RANGE HIGH
1.4
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1158/2159-8290.CD-18-1220
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI BL21(DE3) HUMAN
K-RAS 2, KI-RAS, C-K-RAS, C-KI-RAS
Mutations
P01116 KRAS, KRAS2, RASK2 ESCHERICHIA COLI BL21(DE3) HUMAN
K-RAS 2, KI-RAS, C-K-RAS, C-KI-RAS
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402