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GENERAL
TITLE
CRYO-EM STRUCTURE OF PRC2 BOUND TO COFACTORS AEBP2 AND JARID2 IN THE COMPACT ACTIVE STATE
DATE LAST MODIFIED
18 Dec 2019
RELEASE
24 Jan 2018
OBSOLETE
CLASSIFICATION
GENE REGULATION
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.9
RESOLUTION RANGE LOW
3.9
PUBMED ID
DOI
10.1126/SCIENCE.AAR5700
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 TRICHOPLUSIA NI HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
Q92833 JARID2, JMJ TRICHOPLUSIA NI HUMAN
JUMONJI/ARID DOMAIN-CONTAINING PROTEIN 2
Mutations
Q15910 EZH2, KMT6 TRICHOPLUSIA NI HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Mutations
Q92833 JARID2, JMJ TRICHOPLUSIA NI HUMAN
JUMONJI/ARID DOMAIN-CONTAINING PROTEIN 2
Mutations
Q15910 EZH2, KMT6 TRICHOPLUSIA NI HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Mutations
O75530 EED TRICHOPLUSIA NI HUMAN
HEED,EMBRYONIC ECTODERM DEVELOPMENT PROTEIN,WD PRO ...
Mutations
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 TRICHOPLUSIA NI HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
Q09028 RBBP4, RBAP48 TRICHOPLUSIA NI HUMAN
CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT C,CAF-1 SUBUNI ...
Mutations
-- TRICHOPLUSIA NI HOMO SAPIENS --
Q6ZN18 AEBP2 TRICHOPLUSIA NI HUMAN
ADIPOCYTE ENHANCER-BINDING PROTEIN 2,AE-BINDING PR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402