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GENERAL
TITLE
STRUCTURE BASED DESIGN OF RIP1 KINASE INHIBITORS
DATE LAST MODIFIED
4 Apr 2018
RELEASE
21 Mar 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.52
RESOLUTION RANGE LOW
95.39
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B01647
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q13546 RIPK1, RIP, RIP1 SPODOPTERA FRUGIPERDA HUMAN
CELL DEATH PROTEIN RIP,RECEPTOR-INTERACTING PROTEI ...
Mutations
Q13546 RIPK1, RIP, RIP1 SPODOPTERA FRUGIPERDA HUMAN
CELL DEATH PROTEIN RIP,RECEPTOR-INTERACTING PROTEI ...
Mutations
Q13546 RIPK1, RIP, RIP1 SPODOPTERA FRUGIPERDA HUMAN
CELL DEATH PROTEIN RIP,RECEPTOR-INTERACTING PROTEI ...
Mutations
Q13546 RIPK1, RIP, RIP1 SPODOPTERA FRUGIPERDA HUMAN
CELL DEATH PROTEIN RIP,RECEPTOR-INTERACTING PROTEI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402