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GENERAL
TITLE
HUMAN CYP3A4 BOUND TO AN INHIBITOR
DATE LAST MODIFIED
18 Dec 2019
RELEASE
3 Apr 2019
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
2.65
RESOLUTION RANGE LOW
78.5
PUBMED ID
DOI
10.1021/ACS.BIOCHEM.9B00156

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P08684 CYP3A4, CYP3A3 ESCHERICHIA COLI HUMAN 1,8-CINEOLE 2-EXO-MONOOXYGENASE,ALBENDAZOLE MONOOXYGENASE,ALBENDAZOLE SULFOXIDASE,CYPIIIA3,CYPIIIA4,CHOLESTEROL 25-HYDROXYLASE,CYTOCHROME P450 3A3,CYTOCHROME P450 HLP,CYTOCHROME P450 NF-25,CYTOCHROME P450-PCN1,NIFEDIPINE OXIDASE,QUININE 3-MONOOXYGENASE,TAUROCHENODEOXYCHOLATE 6-ALPHA-HYDROXYLASE HUMAN
1,8-CINEOLE 2-EXO-MONOOXYGENASE,ALBENDAZOLE MONOOX ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402