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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH DARGLITAZONE
DATE LAST MODIFIED
25 Dec 2019
RELEASE
22 May 2019
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/TRANSCRIPTION INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.95
RESOLUTION RANGE LOW
41.02
PUBMED ID
DOI
10.1073/PNAS.1909016116
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P37231 PPARG, NR1C3 ESCHERICHIA COLI BL21(DE3) HUMAN PPAR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP C MEMBER 3 HUMAN
PPAR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP C ME ...
Mutations
P37231 PPARG, NR1C3 ESCHERICHIA COLI BL21(DE3) HUMAN PPAR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP C MEMBER 3 HUMAN
PPAR-GAMMA,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP C ME ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402