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GENERAL
TITLE
RATIONAL MODIFICATION OF VANILLIN DERIVATIVES TO STEREOSPECIFICALLY DESTABILIZE SICKLE HEMOGLOBIN POLYMER FORMATION
DATE LAST MODIFIED
4 Dec 2019
RELEASE
5 Sept 2018
OBSOLETE
CLASSIFICATION
OXYGEN TRANSPORT
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
29.34
PUBMED ID
DOI
10.1107/S2059798318009919
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
P69905 -- -- HUMAN
ALPHA-GLOBIN,HEMOGLOBIN ALPHA CHAIN
Mutations
P68871 -- -- HUMAN
BETA-GLOBIN,HEMOGLOBIN BETA CHAIN
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402