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GENERAL
TITLE
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N49 I.E. 2-((2- CHLOROPHENYL)(2-(1-METHYLPYRROLIDIN-2-YL)ETHOXY)METHYL)THIENO[3,2- B]PYRIDINE-7-CARBOXYLIC ACID
DATE LAST MODIFIED
1 Jan 2020
RELEASE
21 Nov 2018
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.46
RESOLUTION RANGE LOW
33.01
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01219
PDBe
6DQ8
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P29375 | KDM5A, JARID1A, RBBP2, RBP2 | ESCHERICHIA COLI | HUMAN | HISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CONTAININGPROTEIN 1A,RETINOBLASTOMA-BINDING PROTEIN 2,RBBP-2,HISTONEDEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CONTAINING PROTEIN 1A,RETINOBLASTOMA-BINDING PROTEIN 2,RBBP-2 | HUMAN | HISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CO ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402