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6E2N

3D Structure View

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GENERAL
TITLE
ASK1 KINASE DOMAIN COMPLEX WITH INHIBITOR
DATE LAST MODIFIED
17 Oct 2018
RELEASE
19 Sept 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 2 21 21
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1172/JCI99768

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q99683 MAP3K5, ASK1, MAPKKK5, MEKK5 ESCHERICHIA COLI HUMAN
APOPTOSIS SIGNAL-REGULATING KINASE 1,ASK-1,MAPK/ER ...
Mutations
Q99683 MAP3K5, ASK1, MAPKKK5, MEKK5 ESCHERICHIA COLI HUMAN
APOPTOSIS SIGNAL-REGULATING KINASE 1,ASK-1,MAPK/ER ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402