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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE HETERODIMERIC HIF-2 COMPLEX WITH AGONIST M1001
DATE LAST MODIFIED
18 Dec 2019
RELEASE
13 Feb 2019
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/AGONIST
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.85
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1038/S41589-019-0234-5
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P53762 ARNT ESCHERICHIA COLI BL21(DE3) MOUSE ARNT PROTEIN,DIOXIN RECEPTOR,NUCLEAR TRANSLOCATOR,HYPOXIA-INDUCIBLE FACTOR 1-BETA,HIF1-BETA MOUSE
ARNT PROTEIN,DIOXIN RECEPTOR,NUCLEAR TRANSLOCATOR, ...
Mutations
P97481 EPAS1, HIF2A ESCHERICHIA COLI BL21(DE3) MOUSE EPAS-1,HIF-1-ALPHA-LIKE FACTOR,MHLF,HIF-RELATED FACTOR,HRF,HYPOXIA-INDUCIBLE FACTOR 2-ALPHA,HIF2-ALPHA MOUSE
EPAS-1,HIF-1-ALPHA-LIKE FACTOR,MHLF,HIF-RELATED FA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402