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GENERAL
TITLE
GLUCOCORTICOID RECEPTOR IN COMPLEX WITH AZD9567
DATE LAST MODIFIED
21 Mar 2018
RELEASE
21 Feb 2018
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.19
RESOLUTION RANGE LOW
105.72
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B01690
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P04150 NR3C1, GRL TRICHOPLUSIA NI HUMAN GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1F602S, C638D, E684A, W712S HUMAN
GR,NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1F6 ...
Mutations
Q15596 -- -- HUMAN NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,BHLHE75,TRANSCRIPTIONAL INTERMEDIARY FACTOR 2,HTIF2 HUMAN
NCOA-2,CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 75,B ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402