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GENERAL
TITLE
EUKARYOTIC INITIATION FACTOR EIF2B IN COMPLEX WITH ISRIB
DATE LAST MODIFIED
11 Dec 2019
RELEASE
28 Mar 2018
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
4.1
RESOLUTION RANGE LOW
4.1
PUBMED ID
DOI
10.1126/SCIENCE.AAR5129
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q14232 -- -- HUMAN EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT ALPHA HUMAN
EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT ALPHA
Mutations
Q14232 -- -- HUMAN EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT ALPHA HUMAN
EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT ALPHA
Mutations
P49770 EIF2B2, EIF2BB HOMO SAPIENS HUMAN S20I15,S20III15,EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT BETA HUMAN
S20I15,S20III15,EIF-2B GDP-GTP EXCHANGE FACTOR SUB ...
Mutations
P49770 EIF2B2, EIF2BB HOMO SAPIENS HUMAN S20I15,S20III15,EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT BETA HUMAN
S20I15,S20III15,EIF-2B GDP-GTP EXCHANGE FACTOR SUB ...
Mutations
Q9NR50 -- -- HUMAN EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT GAMMA HUMAN
EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT GAMMA
Mutations
Q9NR50 -- -- HUMAN EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT GAMMA HUMAN
EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT GAMMA
Mutations
Q9UI10 -- -- HUMAN EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT DELTA HUMAN
EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT DELTA
Mutations
Q9UI10 -- -- HUMAN EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT DELTA HUMAN
EIF-2B GDP-GTP EXCHANGE FACTOR SUBUNIT DELTA
Mutations
Q13144 -- -- HUMAN -- HUMAN -- Mutations
Q13144 -- -- HUMAN -- HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402