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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE GLUA2 LIGAND-BINDING DOMAIN (S1S2J) IN COMPLEX WITH THE POSITIVE ALLOSTERIC MODULATOR TDPAM01 AT 1.4 A RESOLUTION.
DATE LAST MODIFIED
-
RELEASE
21 Nov 2018
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 2
RESOLUTION RANGE HIGH
1.4
RESOLUTION RANGE LOW
48.603
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B00250
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| P19491 | GRIA2, GLUR2 | ESCHERICHIA COLI , ESCHERICHIA COLI | RAT | GLUR-2,AMPA-SELECTIVE GLUTAMATE RECEPTOR 2,GLUR-B,GLUR-K2,GLUTAMATE RECEPTOR IONOTROPIC,AMPA 2,GLUA2TRANSMEMBRANE REGIONS WERE GENETICALLY REMOVED AND REPLACED WITH AGLY-THR LINKER (RESIDUE 118-119). THE SEQUENCE MATCHESDISCONTINUOUSLY WITH REFERENCE DATABASE (413-527, 653-797). GLY-ALAARE CLONING REMANANTS. | RAT | GLUR-2,AMPA-SELECTIVE GLUTAMATE RECEPTOR 2,GLUR-B, ... | Mutations | |
| P19491 | GRIA2, GLUR2 | ESCHERICHIA COLI , ESCHERICHIA COLI | RAT | GLUR-2,AMPA-SELECTIVE GLUTAMATE RECEPTOR 2,GLUR-B,GLUR-K2,GLUTAMATE RECEPTOR IONOTROPIC,AMPA 2,GLUA2TRANSMEMBRANE REGIONS WERE GENETICALLY REMOVED AND REPLACED WITH AGLY-THR LINKER (RESIDUE 118-119). THE SEQUENCE MATCHESDISCONTINUOUSLY WITH REFERENCE DATABASE (413-527, 653-797). GLY-ALAARE CLONING REMANANTS. | RAT | GLUR-2,AMPA-SELECTIVE GLUTAMATE RECEPTOR 2,GLUR-B, ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402