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GENERAL
TITLE
DDR1, 2-[8-(1H-INDAZOLE-5-CARBONYL)-4-OXO-1-PHENYL-1,3,8- TRIAZASPIRO[4.5]DECAN-3-YL]-N-METHYLACETAMIDE, 1.440A, P1211, RFREE=24.1%
DATE LAST MODIFIED
27 Mar 2019
RELEASE
28 Nov 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.44
RESOLUTION RANGE LOW
43.42
PUBMED ID
DOI
10.1021/ACSCHEMBIO.8B00866
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q08345 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE SPODOPTERA FRUGIPERDA HUMAN EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1,CD167 ANTIGEN-LIKEFAMILY MEMBER A,CELL ADHESION KINASE,DISCOIDIN RECEPTOR TYROSINEKINASE,HGK2,MAMMARY CARCINOMA KINASE 10,MCK-10,PROTEIN-TYROSINEKINASE 3A,PROTEIN-TYROSINE KINASE RTK-6,TRK E,TYROSINE KINASE DDR,TYROSINE-PROTEIN KINASE CAK HUMAN
EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1,CD167 ANTIG ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402