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GENERAL
TITLE
DEVELOPMENT AND CHARACTERIZATION OF A CNS-PENETRANT BENZHYDRYL HYDROXAMIC ACID CLASS IIA HISTONE DEACETYLASE INHIBITOR
DATE LAST MODIFIED
26 Dec 2018
RELEASE
5 Dec 2018
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32
RESOLUTION RANGE HIGH
2.15
RESOLUTION RANGE LOW
45.7
PUBMED ID
DOI
10.1016/J.BMCL.2018.11.009

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P56524 HDAC4, KIAA0288 ESCHERICHIA COLI HUMAN HD4 HUMAN
HD4
Mutations
P56524 HDAC4, KIAA0288 ESCHERICHIA COLI HUMAN HD4 HUMAN
HD4
Mutations
P56524 HDAC4, KIAA0288 ESCHERICHIA COLI HUMAN HD4 HUMAN
HD4
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402