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GENERAL
TITLE
ALPHA-GALACTOSIDASE MUTANT D378A FROM THERMOTOGA MARITIMA IN COMPLEX WITH INTACT CYCLOHEXENE-BASED CARBASUGAR MIMIC OF GALACTOSE WITH 3,5 DIFLUOROPHENYL LEAVING GROUP
DATE LAST MODIFIED
-
RELEASE
22 Aug 2018
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
69.5
PUBMED ID
DOI
10.1038/S41467-018-05702-7

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
G4FEF4 GALA, TM_1192, TMARI_1199 ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' -- MELIBIASEDISORDERED AND COULD NOT BE MODELLED IN THE STRUCTURE. THIS PROTEINHAS A CATALYTICALLY IMPAIRED D387A MUTATION WHICH AIDED CAPTURE OFTHE COMPLEX WITH INTACT INHIBITOR. --
MELIBIASEDISORDERED AND COULD NOT BE MODELLED IN T ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402