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GENERAL
TITLE
CDK2/CYCLIN A2 IN COMPLEX WITH PYRAZOLO[4,3-D]PYRIMIDINE INHIBITOR LGR4455
DATE LAST MODIFIED
22 May 2019
RELEASE
1 May 2019
OBSOLETE
CLASSIFICATION
CELL CYCLE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.15
RESOLUTION RANGE LOW
48
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B00189

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P24941 CDK2, CDKN2 ESCHERICHIA COLI HUMAN CELL DIVISION PROTEIN KINASE 2,P33 PROTEIN KINASE HUMAN
CELL DIVISION PROTEIN KINASE 2,P33 PROTEIN KINASE
Mutations
P20248 CCNA2, CCN1, CCNA ESCHERICHIA COLI HUMAN CYCLIN-A,CYCLIN A HUMAN
CYCLIN-A,CYCLIN A
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402