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GENERAL
TITLE
CRYSTAL STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (MELK) IN COMPLEX WITH DORSOMORPHIN (COMPOUND C)
DATE LAST MODIFIED
19 Jun 2019
RELEASE
29 May 2019
OBSOLETE
CLASSIFICATION
ONCOPROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.24
RESOLUTION RANGE LOW
48.672
PUBMED ID
DOI
10.1016/J.ABB.2019.05.014
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q14680 MELK, KIAA0175 ESCHERICHIA COLI HUMAN HMELK,PROTEIN KINASE EG3,PEG3 KINASE,PROTEIN KINASE PK38,HPK38,TYROSINE-PROTEIN KINASE MELK HUMAN
HMELK,PROTEIN KINASE EG3,PEG3 KINASE,PROTEIN KINAS ...
Mutations
Q14680 MELK, KIAA0175 ESCHERICHIA COLI HUMAN HMELK,PROTEIN KINASE EG3,PEG3 KINASE,PROTEIN KINASE PK38,HPK38,TYROSINE-PROTEIN KINASE MELK HUMAN
HMELK,PROTEIN KINASE EG3,PEG3 KINASE,PROTEIN KINAS ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402