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GENERAL
TITLE
1,1-DIHETEROCYCLIC ETHYLENES DERIVED FROM QUINALDINE AND CARBAZOLE AS NEW TUBULIN POLYMERIZATION INHIBITORS: SYNTHESIS, METABOLISM, AND BIOLOGICAL EVALUATION
DATE LAST MODIFIED
13 Mar 2019
RELEASE
19 Dec 2018
OBSOLETE
CLASSIFICATION
TRANSPORT PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.745
RESOLUTION RANGE LOW
47.65
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01386
PDBe
6H9B
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonyms | Actions | ||
|---|---|---|---|---|---|---|---|---|
| -- | -- | OVIS ARIES | -- | OVIS ARIES | -- | |||
| -- | -- | OVIS ARIES | -- | OVIS ARIES | -- | |||
| -- | -- | OVIS ARIES | -- | OVIS ARIES | -- | |||
| -- | -- | OVIS ARIES | -- | OVIS ARIES | -- | |||
| P63043 | STMN4 | ESCHERICHIA COLI | RAT | STATHMIN-LIKE PROTEIN B3,RB3 | RAT | STATHMIN-LIKE PROTEIN B3,RB3 | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402